Aplastic Anemia Cause

Aplastic anemia is a serious condition and the incidence reportedly occurs in three separate peaks: when people are 2-5 years old, 20-25 years old and 55-60 years old.Aplastic anemia is a serious and potentially fatal condition defined as a medical condition in which there is a reduction in the number of blood cells and platelets in the body.

The conditions affects the ability of blood cells within the body to produce in a healthy manner. The white and red blood cells and platelets are affected by the aplastic anemia and begin produce erratically.

Etiology of Aplastic Anemia Incidences

According to reports, an estimated 70% of aplastic anemia cases are idiopathic. However the other percentage of cases that occur are caused by:

  • Hereditary Reasons- Fanconi Anemia, Dyskeratosis Congenital and Schwachman-Diamond syndrome can all lead to aplastic anemia
  • Acquired Cases- Direct stem cell destruction, certain medications and  infections
  • Exposure to benzene- Benzene and other toxic chemicals can causes aplastic anemia over time
  • Immune Disorders- Hereditary and acquired immune disorders can lead to the condition

Receiving an Aplastic Anemia Diagnosis

Although the incidence of aplastic anemia is not very common, people are affected yearly by this health condition. A definitive diagnosis for aplastic anemia can be made by acquiring a bone marrow biopsy. A biopsy typically takes place in a lab that includes CBC with platelets and smear, drug screen, viral serologies, serum folate and B12.

A bone marrow biopsy may also be used as an effective way of determining whether a person has profound hypocelularity and malignant fibrosis or infiltrates. For a healthy outcome, the hematopoetic cells should be normal and not be megaloblastic.

Receiving a Treatment for Aplastic Anemia

When a person is exposed to any agents known to cause aplastic anemia, such as benzene or other toxic chemicals, doctors want to make sure these agents are removed from the person’s life immediately. Particularly after a diagnosis is made since exposure can only worsen the patient’s health.

However, in some cases the damage to the bone marrow is already irreversible and initial treatment for aplastic anemia consists of supportive care, blood transfusions and the overall limitation of infectious exposures.

While more definitive therapy consists of hematopoietic stem cell transplantation. Research shows that matched sibling donor transplants have a cure rate of 60 to 70%.

Do you know someone that is suffering from aplastic anemia due to exposure to benzene? If so, contact an experienced benzene lawyer for legal support and an evaluation of your claim.

Tags: benzene exposure, aplastic anemia treatment, benzene leukemia, aplastic anemia causes, aplastic anemia

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